epitope mapping within an internal region of TSPEAR of human origin
Modification Notes
TSPEAR, also known as C21orf9, is a 669 amino acid secreted protein. Expressed as two isoforms produced by alternative splicing, TSPEAR contains one Thrombospondin N-terminal domain and seven EAR (epilepsy-associated repeat) domains. EAR domains are found in several proteins, including TSPEAR, encoded by genes that map within chromosome regions associated with seizure disorders. It is thought that the EAR domain plays a role in the pathogenesis of epilepsy by either binding to an unknown epileptic ligand or interfering with axon synaptogenesis.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TSPEAR of h and r origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of TSPEAR of human origin
Tissue Specificity
epitope mapping within an internal region of TSPEAR of human origin
Western blot analysis of TSPEAR expression in human PBL whole cell lysate.
Application Notes
recommended for detection of TSPEAR of h and r origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.