| Product Name | BCORL2 Antibody (P-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of BCORL2 of human origin |
| Modification Notes | Bcl-6, a transcriptional repressor, can promote or inhibit apoptosis depending on the cell type and also plays an important role in normal immune responses. Bcl-6 negatively regulates NF˚B expression, thereby inhibiting NF˚B-mediated cellular functions and is frequently found to be deregulated in non-Hodgkin’s lymphoma. BCoR protein family members associate with histone deacetylases (HDACs) to transcriptionally repress Bcl-6. BCORL2 (BCL-6 corepressor-like protein 2) is a 145 amino acid protein that is a homolog of BCoR and, by similarity, most likely functions to regulate the transcription of Bcl-6 by inhibiting gene expression when recruited to promoter regions. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of BCORL2 of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of BCORL2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of BCORL2 of human origin |
| Entrez Gene | 286554 |
|---|
| Application Notes | recommended for detection of BCORL2 of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
