Application
Western blot analysis of RIOK1 expression in A375 whole cell lysate.| Product Name | RIOK1 Antibody (C-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of RIOK1 of human origin by WB, IP and ELISA |
| Modification Notes | The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. RIOK1 (RIO kinase 1), also known as RIO1 or AD034, is a 568 amino acid protein that contains one protein kinase domain and belongs to the RIO subfamily of atypical Ser/Thr protein kinases. Existing as two alternatively spliced isoforms, RIOK1 functions to catalyze the ATP-dependent phosphorylation of target proteins and is thought to play an important role in ribosome biogenesis and cell cycle progression. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of RIOK1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of RIOK1 of human origin by WB, IP and ELISA |
| Entrez Gene | 83732 |
|---|
Application
Western blot analysis of RIOK1 expression in A375 whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
