TRIM62 (tripartite motif-containing 62) is a 475 amino acid protein that belongs to the TRIM/RBCC (Ring finger, B box, coiled-coil) family. TRIM62 contains one B box-type zinc finger, one SPRY domain and one RING-type zinc finger; a motif that has zinc-chelating activity and is involved in mediating protein-protein and protein-DNA interactions. As a member of the TRIM/RBCC family, TRIM62 may function in transcriptional regulation, cell transformation and carcinogenesis. In addition, TRIM62 expression can affect the entry of murine leukemia virus (MLV) and human immunodeficiency virus 1 (HIV). As is suggested by the inhibition of HIV and MLV release in TRIM62-depleted cells, TRIM62 may play a role in the cellular pathways that are essential for efficient virus release.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of TRIM62 of mouse, rat, human and canine origin by WB, IP and ELISA: