Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF385A (Zinc finger matrin-type protein 385A), also known as HZF (Hematopoietic zinc finger protein), RZF (Retinal zinc finger protein) or ZNF385, is a 366 amino acid protein that contains three matrin-type zinc fingers. The matrin-type zinc finger, which is very similar in structure to the classical DNA-binding C2H2 zinc finger, was first identified in the protein matrin-3. The matrin-type zinc finger has also been identified in several spliceosome RNA-binding proteins, suggesting a role in pre-mRNA binding. ZNF385A is expressed predominantly in the retina and is localized to the nucleus as well as the cytoplasm. Two isoforms of ZNF385A exists due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of ZNF382 of human and canine origin by WB, IP and ELISA: