Application
Western blot analysis of ARID3B expression in K-562 whole cell lysate.Application
Western blot analysis of ARID3B expression in human fetal thymus extract.| Product Name | ARID3B Antibody (E-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ARID3B of human origin |
| Modification Notes | ARID3B (AT rich interactive domain 3B), also known as DRIL2 or BDP (Bright and dead ringer protein) in humans and Bright-like (for B cell regulator of IgH transcription-like) in mice, is one of the mammalian homologs of the Drosophila Dri (dead ringer) protein. ARID3B also shares homology with RBP1 and RBP2 (Retinoblastoma binding proteins 1 and 2). ARID3B represents a member of a unique family of DNA-binding proteins that have roles in cell lineage gene regulation, cell cycle control, embryonic patterning and transcriptional regulation. ARID3B localizes to the nucleus and contains an AT-rich interactive domain (ARID) which has DNA-binding capabilities. Functioning as a transcription factor, ARID3B associates in a heterodimer with the related protein ARID3A and is believed to play an important role in neural crest survival during embryogenesis. In addition, ARID3B may participate in malignant transformation and neuroblastoma growth, suggesting a possible use of ARID3B as a tumor marker for neuroblastoma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ARID3B of human and canine origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ARID3B of human origin |
|---|---|
| Tissue Specificity | raised against ARID3B of human origin |
| Entrez Gene | 10620 |
|---|
Application
Western blot analysis of ARID3B expression in K-562 whole cell lysate.
Application
Western blot analysis of ARID3B expression in human fetal thymus extract.| Application Notes | recommended for detection of ARID3B of human and canine origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
