Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix, uterine showing cytoplasmic staining of glandular cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix, uterine showing cytoplasmic staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of INSL5 expression in NIH/3T3 whole cell lysate.| Product Name | INSL5 Antibody (H-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 26-135 raised against INSL5 of human origin |
| Modification Notes | INSL5 (Insulin-like peptide INSL5, Relaxin/Insulin-like protein) is a 135 amino acid protein encoded by the human gene INSL5. The insulin gene superfamily hormones modulate metabolism, cell growth and tissue-specific functions. Members of this superfamily are characterized by a signal peptide, a B chain, a connecting C chain and an A chain. Insulin-like peptides (INSL proteins), also designated relaxin-like factors, are mostly secreted proteins that are expressed mainly in testis, placenta, uterus or prenatal tissues. INSL5 shares 40% and 59% sequence homology with human RLN1 and mouse Insl5, respectively, and contains a dibasic cleavage site between the B and C chains. INSL5 exists as a heterodimer of a B chain and an A chain which are linked by two disulfide bonds. INSL5 is thought to play a role in gut contractility or in thymic development and regulation, as it demonstrates predominant expression in the rectum and intermediate expression in the uterus and ascending and descending colon. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of INSL5 precursor, A chain and B chain of human origin by WB, IP, I, IHC(P)F and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 26-135 raised against INSL5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 26-135 raised against INSL5 of human origin |
| Entrez Gene | 10022 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix, uterine showing cytoplasmic staining of glandular cells at low magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix, uterine showing cytoplasmic staining of glandular cells at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of INSL5 expression in NIH/3T3 whole cell lysate.| Application Notes | recommended for detection of INSL5 precursor, A chain and B chain of human origin by WB, IP, I, IHC(P)F and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
