epitope corresponding to amino acids 1-200 representing full length IL-28 of human origin
Modification Notes
The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. As new cytokines are molecularly characterized, they are assigned an IL number to maintain a standard nomenclature. The interleukins are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-28 and IL-29 are induced by viral infection and show antiviral activity. They are class II cytokines that stimulate their response through a distinct heterodimeric receptor. IL-28 may play a role in antiviral immunity through up-regulation of MHC class I antigen expression. IL-29 stimulates an identical response as IFN-alpha but utilizes a different receptor. These interleukins may be useful against chronic viral hepatitis.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of IL-28 and IL-29 of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-200 representing full length IL-28 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-200 representing full length IL-28 of human origin