Application
Western blot analysis of CA VIII expression in rat cerebellum (A) and mouse brain (B) tissue extracts.Application
Western blot analysis of CA VIII expression in non-transfected: (A) and mouse CA VIII transfected: (B) 293T whole cell lysates.Application
Western blot analysis of CA VIII expression in mouse cerebellum (A) and mouse brain (B) tissue extracts.| Product Name | CA VIII Antibody (H-100) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-100 mapping at the N-terminus of CA VIII of human origin |
| Modification Notes | Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide. CAs show extensive diversity in their distribution and subcellular localization. They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VIII, also referred to as carbonic anhydrase-related protein VIII (CA-RP VIII), is a member of the carbonic anhydrase family that lacks the Zn-binding motif essential for carbonic anhydrase activity. For this reason, CA VIII does not exhibit catalytic activity but instead may be important in synaptic vesicle formation and transport. In addition, CA VIII may be involved in the invasiveness of non-small cell lung carcinomas and may also play a role in the growth of colon cancer cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CA VIII of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-100 mapping at the N-terminus of CA VIII of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-100 mapping at the N-terminus of CA VIII of human origin |
| Entrez Gene | 767 |
|---|
Application
Western blot analysis of CA VIII expression in rat cerebellum (A) and mouse brain (B) tissue extracts.
Application
Western blot analysis of CA VIII expression in non-transfected: (A) and mouse CA VIII transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of CA VIII expression in mouse cerebellum (A) and mouse brain (B) tissue extracts.| Application Notes | recommended for detection of CA VIII of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
