| Product Name | MAS1 Antibody (H-117) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-117 mapping at the N-terminus of MAS1 of human origin |
| Modification Notes | The proto-oncogene MAS1 is a G protein-coupled receptor located on the plasma membrane. In transfected NIH/3T3 cells, MAS1 has a weak focus-inducing activity. MAS1 is an antagonist of the Angiotensin II type 1 (AT1) receptor, inhibiting the actions of Angiotensin II. MAS1 localizes to cardiomyocytes of the heart in mice. Mice deficient for MAS1 demonstrate a lower systolic tension and heart rate. The proper structure and function of the heart may be impaired by nonfunctional MAS1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MAS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-117 mapping at the N-terminus of MAS1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-117 mapping at the N-terminus of MAS1 of human origin |
| Entrez Gene | 4142 |
|---|
| Application Notes | recommended for detection of MAS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
