recommended for detection of ARX of mouse and human origin by WB, IP and ELISA
Modification Notes
The aristaless-related homeobox (ARX) gene encodes a protein of 562 amino acids which contains two conserved domains, a C-peptide (or aristaless domain) and the prd-like class homeobox domain. ARX is a member of the group-II aristaless-related protein family and is expressed in fetal and adult brain and skeletal muscle. It may be involved in the differentiation and maintenance of neuronal cell types in the human central nervous system. Defects in the ARX gene are associated with various disorders including, X-linked mental retardation (XLMR), X-linked lissencephaly with abnormal genitalia (XLAG), X-linked infantile spasm syndrome (ISSX), X-linked myoclonic epilepsy with intellectual disability and spasticity (XMEDS), Partington syndrome (PRTS), non-specific X-linked mental retardation type 36 (MRX36), and non-specific X-linked mental retardation type 54 (MRX54).
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ARX of mouse and human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ARX of mouse and human origin by WB, IP and ELISA