Application
Western blot analysis of TMEM40 expression in NIH/3T3 whole cell lysate.| Product Name | TMEM40 Antibody (A-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of TMEM40 of human origin |
| Modification Notes | Transmembrane protein 40 (TMEM40) is a 233 amino acid multi-pass membrane protein. Existing as two isoforms, TMEM40 is localized to chromosome 3p25.1 and is believed to play a role in collagen induced arthritis (CIA). Chromosome 3 is made up of about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells, and key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMEM40 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TMEM40 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TMEM40 of human origin |
| Entrez Gene | 55287 |
|---|
Application
Western blot analysis of TMEM40 expression in NIH/3T3 whole cell lysate.| Application Notes | recommended for detection of TMEM40 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TMEM family members also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
