recommended for detection of ZNF432 of human origin by WB, IP and ELISA
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF432 (zinc finger protein 432) is a 652 amino acid nuclear protein containing sixteen C2H2-type zinc fingers and one KRAB domain. One of several members of the krüppel C2H2-type zinc-finger protein family, ZNF432 is thought to be involved in transcriptional regulation events. ZNF432 has been identified as a nitroprotein and is encoded by a gene mapping to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ZNF432 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ZNF432 of human origin by WB, IP and ELISA