| Product Name | TMTC3 Antibody (N-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The tetratricopeptide repeat (TPR) motif is a degenerate, 34 amino acid sequence found in many proteins that acts to mediate protein-protein interactions in various pathways. At the sequence level, there can be up to 16 tandem TPR repeats, each of which has a helix-turn-helix shape that stacks on other TPR repeats to achieve ligand binding specificity. TMTC3 (transmembrane and tetratricopeptide repeat containing 3), also known as SMILE, is a 915 amino acid multi-pass membrane protein belonging to the TMTC family and contains ten TPR repeats. Existing as two alternatively spliced isoforms, TMTC3 is encoded by a gene located on human chromosome 12q21.32. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TMTC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with TMTC1, TMTC2 or TMTC4 also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of TMTC3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of TMTC3 of human origin |
| Entrez Gene | 160418 |
|---|
| Application Notes | recommended for detection of TMTC3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with TMTC1, TMTC2 or TMTC4 also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
