Application
Western blot analysis of ZNF264 expression in Jurkat whole cell lysate.| Product Name | ZNF264 Antibody (E-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF264 is a 627 amino acid protein belonging to the Krüppel C2H2-type zinc finger protein family. ZNF264 has one KRAB domain and thirteen C2H2 zinc fingers. Due to the presence of these domains, ZNF264 is thought to be involved in transcriptional regulation. ZNF264 is phosphorylated by either ATM or ATR upon DNA damage, possibly indicating a role in DNA repair. Localized to the nucleus, ZNF264 is highly expressed in testis, ovary, kidney, thymus, placenta, brain, lung and prostate and is present at lower levels in liver, heart, spleen, pancreas, small intestine and skeletal muscle. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ZNF264 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF264 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF264 of human origin |
| Entrez Gene | 9422 |
|---|
Application
Western blot analysis of ZNF264 expression in Jurkat whole cell lysate.| Application Notes | recommended for detection of ZNF264 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
