Application
Western blot analysis of MGC4618 expression in Hep G2 whole cell lysate.| Product Name | MGC4618 Antibody (J-25) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | MGC4618, also known as TMEM175 (transmembrane protein 175), is a 504 amino acid multi-pass membrane protein that is expressed as two isoforms produced by alternative splicing. The gene encoding MGC4618 maps to chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The MGC4618 gene product has been provisionally designated MGC4618 pending further characterization. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of MGC4618 of mouse, rat and human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against MGC4618 of human origin |
|---|---|
| Tissue Specificity | raised against MGC4618 of human origin |
| Entrez Gene | 84286 |
|---|
Application
Western blot analysis of MGC4618 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of MGC4618 of mouse, rat and human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
