| Product Name | HVCN1 Antibody (H-113) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | HVCN1 (hydrogen voltage-gated channel 1), also known as HV1 or voltage sensor domain-only protein, is a 273 amino acid protein belonging to the hydrogen channel family. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. This proton conductance allows for the oxidative burst that is used for microbial killing by phagocytic leukocytes. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 is enriched in immune tissues and is expressed as three isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HVCN1 isoforms 1-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 161-273 mapping at the C-terminus of HVCN1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 161-273 mapping at the C-terminus of HVCN1 of human origin |
| Entrez Gene | 84329 |
|---|
| Application Notes | recommended for detection of HVCN1 isoforms 1-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
