Application
Western blot analysis of FGFR-5 expression in non-transfected: (A) and human FGFR-5 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of FGFR-5 expression in non-transfected: (A) and mouse FGFR-5 transfected: (B) 293T whole cell lysates.| Product Name | FGFR-5 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Acidic and basic fibroblast growth factors (FGFs) are members of a family of multifunctional polypeptide growth factors that stimulate proliferation of c150ells of mesenchymal, epithelial and neuro-ectodermal origin. Like other growth factors, FGFs act by binding and activating specific cell surface receptors. A total of six members of the FGF receptor family have been identified and cloned. These include the Flg receptor (FGFR-1), the Bek receptor (FGFR-2) and FGFR-3–6. These receptors usually contain an extracellular ligand-binding region containing three immunoglobulin-like domains, a transmembrane domain and a cytoplasmic tyrosine kinase domain. However, FGFR-5 lacks the cytoplasmic kinase domain. FGFR-5 is expressed in a broad range of tissues, including kidney, brain and lung. It is preferentially expressed in pancreas, where it may play a role in the regulation of some pancreatic function. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FGFR-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 31-330 mapping within an N-terminal extracellular domain of FGFR-5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 31-330 mapping within an N-terminal extracellular domain of FGFR-5 of human origin |
| Entrez Gene | 53834 |
|---|
Application
Western blot analysis of FGFR-5 expression in non-transfected: (A) and human FGFR-5 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of FGFR-5 expression in non-transfected: (A) and mouse FGFR-5 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of FGFR-5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
