Application
Western blot analysis of SRPK1 expression in non-transfected: (A) and mouse SRPK1 transfected: (B) 293T whole cell lysates.| Product Name | SRPK1 Antibody (H-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 176-215 mapping within an internal region of SRPK1 of human origin |
| Modification Notes | Arginine/serine-rich (RS) domain-containing proteins and their phosphorylation by specific protein kinases constitute control circuits to regulate both constitutive and alternative pre-mRNA splicing and coordinate splicing with transcription in cells. Two SR protein-specific kinases (SRPK, also designated SFRSK), SRPK1 and SRPK2, are highly specific for the phosphorylation of these RS proteins, thereby contributing to splicing regulation. SRPK1 plays a role in the condensation of sperm chromatin. SRPK2 has a stringent preference for SR dipeptides and contains a proline-rich sequence at its amino terminus. Both SRPK1 and SRPK2 are highly expresed in testis. SRPK1 is found exclusively in pancreas and SRPK2 is found exclusively in brain and lung. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SRPK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 176-215 mapping within an internal region of SRPK1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 176-215 mapping within an internal region of SRPK1 of human origin |
| Entrez Gene | 6732 |
|---|
Application
Western blot analysis of SRPK1 expression in non-transfected: (A) and mouse SRPK1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SRPK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
