| Product Name | Septin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Septin 11 of human origin |
| Modification Notes | The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others that are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. Septin 6 is a widely expressed cytoplasmic protein that contains an ATP-GTP binding motif and three nuclear targeting sequences in its C-terminus. Septin 8 interacts with both Septin 5 and cell division cycle related-1 (CDCrel-1), and may play an important role in the functional regulation of hPFTAIRE1, a member of the Cdc2-related kinase family that is localized to the cytoplasm. Like other septin family members, Septin 10, Septin 11 and Septin 14 display GTP-binding and GTPase activity and are suggested to play a role in cytokinesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Septin 6, 8, 10, 11 and 14 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Septin 11 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Septin 11 of human origin |
| Application Notes | recommended for detection of Septin 6, 8, 10, 11 and 14 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
