| Product Name | TSHβ Antibody (FL-138) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-138 representing full length TSHβ of human origin |
| Modification Notes | Various hormones are secreted from the anterior pituitary during development and growth, including thyroid-stimulating hormone (TSH, also known as thyrotropin), follicle-stimulating hormone (FSH) and leutinizing hormone (LH). TSH, FSH, and LH are heterodimers formed from a common å chain and a unique ∫ chain. TSH is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH∫ is regulated by thyroid hormone (T3) and various retinoid compounds. TSH∫ binds to the thyroid-stimulating hormone receptor (TSHR), which plays a major role in regulating thyroid function. TSHR is thought to exist in multiple glycosylation states. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TSHβ and, to a lesser extent, Lutropin β of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-138 representing full length TSH&beta of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-138 representing full length TSHβ of human origin |
| Entrez Gene | 7252 |
|---|
| Application Notes | recommended for detection of TSHβ and, to a lesser extent, Lutropin β of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
