epitope corresponding to amino acids 179-218 mapping within an internal region of AQP9 of human origin
Modification Notes
Human AQP9 (Aquaporin 9) is a 295 amino acid protein that allows passage of a wide variety of noncharged solutes and stimulates osmotic water permeability. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0 through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation, and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of AQP9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 179-218 mapping within an internal region of AQP9 of human origin
Tissue Specificity
epitope corresponding to amino acids 179-218 mapping within an internal region of AQP9 of human origin
Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.
Application
Western blot analysis of human recombinant AQP9 fusion protein.
Application Notes
recommended for detection of AQP9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.