Application
Western blot analysis of Layilin expression in IMR-32 whole cell lysate.Application
Western blot analysis of Layilin expression in rat brain tissue extract.| Product Name | Layilin Antibody (H-132) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 251-382 mapping within a C-terminal cytoplasmic domain of Layilin of human origin |
| Modification Notes | The actin cytoskeleton is crucial for cell shape and motility. The interactions between the cell membrane and actin filaments are important for many cellular processes. Layilin is a widely expressed integral membrane hyaluronan receptor that interacts with the ERM protein family of cytoskeletal membrane linker molecule members, including talin, ezrin, moesin, and radixin. Layilin plays an important role in cell adhesion and motility. Layilin is important for the maintenance of the cortical structure in the cell because it mediates signals from the extracellular matrix to the cytoskeleton. In spreading cells, Layilin acts as a membrane-binding site for talin in the peripheral ruffles, and it may play a role in the migration of cells to a wound site. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Layilin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 251-382 mapping within a C-terminal cytoplasmic domain of Layilin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 251-382 mapping within a C-terminal cytoplasmic domain of Layilin of human origin |
Application
Western blot analysis of Layilin expression in IMR-32 whole cell lysate.
Application
Western blot analysis of Layilin expression in rat brain tissue extract.| Application Notes | recommended for detection of Layilin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
