| Product Name | Syntaxin 19 Antibody (S-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of Syntaxin 19 of human origin |
| Modification Notes | Syntaxins, a family of proteins involved in the fusion of synaptic vesicles with the plasma membrane, display broad tissue distribution and contain C-terminal hydrophobic domains that direct them to their respective intracellular compartments. Syntaxin 19, also known as STX19, is a 294 amino acid peripheral membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the syntaxin family, suggesting a role in synaptic vesicle fusion. The gene encoding Syntaxin 19 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Syntaxin 19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Syntaxin family members also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Syntaxin 19 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Syntaxin 19 of human origin |
| Entrez Gene | 415117 |
|---|
| Application Notes | recommended for detection of Syntaxin 19 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other Syntaxin family members also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
