recommended for detection of ARGFX of human origin by WB, IP and ELISA
Modification Notes
ARGFX (arginine-fifty homeobox) is a 315 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in testis and in undifferentiated embryonic cells, ARGFX belongs to the paired homeobox family and is thought to function as a transcription factor, possibly playing a role in early embryonic development. The gene encoding ARGFX maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of ARGFX of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of ARGFX of human origin by WB, IP and ELISA