epitope mapping within an extracellular domain of TSPAN7 of human origin
Modification Notes
Tetraspanins are a group of hydrophobic membrane proteins that interact with a wide variety of proteins including intracellular signaling molecules, integrins and membrane receptors. TSPAN7 (tetraspanin 7), also known as MXS1 (membrane component chromosome X surface marker 1) or TM4SF2 (transmembrane 4 superfamily member 2), is a 249 amino acid multi-pass membrane protein belonging to the tetraspanin (TM4SF) family of transmembrane proteins. TSPAN7 is believed to play a role in cell motility and cell proliferation. The gene that encodes TSPAN7 maps to human chromosome X and defects in this gene are a cause of mental retardation X-linked type 58 (MRX58), which is characterized by dramatically below average general intellectual functioning.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TSPAN7 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TSPAN family members also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an extracellular domain of TSPAN7 of human origin
Tissue Specificity
epitope mapping within an extracellular domain of TSPAN7 of human origin
Western blot analysis of TSPAN7 expression in CCRF-CEM (A), K-562 (B), Jurkat (C) and M1 (D) whole cell lysates.
Application Notes
recommended for detection of TSPAN7 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other TSPAN family members also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.