Application
Western blot analysis of SULT1A3 expression in non-transfected: (A) and human SULT1A3 transfected: (B) 293T whole cell lysates.| Product Name | SULT1A3/1A4 Antibody (A-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against recombinant SULT1A3/1A4 protein of human origin |
| Modification Notes | SULT1A3 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3) and SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) are identical proteins (referred to simply as SULT1A3/1A4) that are 295 amino acids in length and localize to the cytoplasm. Expressed in brain, liver, colon, lung, placenta, kidney and spleen tissue, SULT1A3/1A4 exists as a homodimer that functions to catalyze the sulfate conjugation of phenolic and catechol drugs, as well as neurotransmitters, including Serotonin, dopamine and norepinephrine. Multiple isoforms of SULT1A3/1A4 exist due to alternative splicing events. The genes encoding SULT1A3 and SULT1A4 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC |
| recommended for detection of SULT1A3/1A4 of human origin and SULT1A1 of mouse and rat origin by WB, IP, IF and IHC(P): |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against recombinant SULT1A3/1A4 protein of human origin |
|---|---|
| Tissue Specificity | raised against recombinant SULT1A3/1A4 protein of human origin |
| Entrez Gene | 6818 |
|---|
Application
Western blot analysis of SULT1A3 expression in non-transfected: (A) and human SULT1A3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of SULT1A3/1A4 of human origin and SULT1A1 of mouse and rat origin by WB, IP, IF and IHC(P): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
