| Product Name | MSE55 Antibody (H-94) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 126-219 mapping within an internal region of MSE55 of human origin |
| Modification Notes | MSE55 also known as Borg5 or binder of Rho GTPases 5) is a Cdc42 effector protein that induces long cellular extensions in fibroblasts (1-5). MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule (1-4). An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42 (1-4). MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells (5). MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling (5). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MSE55 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 126-219 mapping within an internal region of MSE55 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 126-219 mapping within an internal region of MSE55 of human origin |
| Entrez Gene | 11135 |
|---|
| Application Notes | recommended for detection of MSE55 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
