epitope corresponding to amino acids 1-94 mapping at the N-terminus of SKRP1 of human origin
Modification Notes
Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The stress-activated protein kinase (SAPK) pathway-regulating phosphatase 1 (SKRP1) binds to MAP kinase MKK-7 to regulate JNK.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SKRP1 of mouse, rat, equine, bovine and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-94 mapping at the N-terminus of SKRP1 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-94 mapping at the N-terminus of SKRP1 of human origin
recommended for detection of SKRP1 of mouse, rat, equine, bovine and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.