| Product Name | ANP32A/B Antibody (H-163) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-163 mapping at the N-terminus of ANP32B of human origin |
| Modification Notes | Protein phosphatase 2A (PP2A) is a major mammalian serine/threonine phosphatase that regulates diverse cellular processes. ANP32A, also known as Inhibitor 1 of PP2A (I1PP2A) is a heat-stable cytoplasmic and nuclear protein that functions as an inhibitor of cellular PP2A phosphatase activity. ANP32B (acidic (leucine-rich) nuclear phosphoprotein 32 family, member B), also designated PHAPI2, SSP29 or APRIL, is a 251 amino acid protein that localizes to the nucleus and contains four LRR (leucine-rich repeat) motifs. Expressed in placenta, heart, pancreas, lung, prostate, spleen and thymus, ANP32B exists as a multifunctional protein that plays an essential role in cell cycle progression and cell survival and is required for the G1 to S phase transition. Additionally, ANP32B functions as an anti-apoptotic factor that inhibits the activity of caspase-3, a protein that is crucial for the successful execution of apoptotic events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ANP32A and ANP32B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-163 mapping at the N-terminus of ANP32B of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-163 mapping at the N-terminus of ANP32B of human origin |
| Entrez Gene | 10541 |
|---|
| Application Notes | recommended for detection of ANP32A and ANP32B of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
