| Product Name | MBL-A Antibody (M-54) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 97-150 mapping within an internal region of MBL-A of mouse origin |
| Modification Notes | MBL-A, also known as Mbl1 (mannose-binding lectin (protein A) 1) or RaRF p28B, is a 239 amino acid mouse protein that is localized predominately to the golgi apparatus and the rough endoplasmic reticulum and contains one collagen-like domain and one C-type lectin domain. Existing in an oligomeric complex composed of six homotrimers, MBL-A functions to bind N-acetylglucosamine and mannose in a Ca2+-dependent manner and, via this interaction, is able to activate the classical complement pathway, thereby providing host defense against invasive pathogens. Due to its involvement in the innate immune system, MBL-A is involved in the pathogenesis of a variety of afflictions, including diabetes, acute septic peritonitis, asthma, cancer and bacterial and viral infections. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MBL-A of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 97-150 mapping within an internal region of MBL-A of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 97-150 mapping within an internal region of MBL-A of mouse origin |
| Entrez Gene | 17194 |
|---|
| Application Notes | recommended for detection of MBL-A of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
