| Modification Notes |
The sodium-coupled neutral amino acid transporters (SNAT) of the SLC38 gene family include System A subtypes SNAT1, SNAT2 and SNAT4 and System N subtypes SNAT3 and SNAT5. The SLC38 transporters are essential for the uptake of nutrients, energy production, metabolism, detoxification, and the cycling of neurotransmitters. SNAT6 (sodium-coupled neutral amino acid transporter 6), also known as Solute carrier family 38 member 6 and N-system amino acid transporter 1, is a 456 amino acid multi-pass membrane protein that is considered to be a probable sodium-coupled neutral amino acid transporter that is widely expressed in brain. There are two isoforms of SNAT6 that are produced as a result of alternative splicing events. |