Application
Western blot analysis of HMGN3 expression in non-transfected: (A) and human HMGN3 transfected: (B) 293T whole cell lysates.| Product Name | HMGN3 Antibody (P-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of HMGN3 of human origin |
| Modification Notes | HMGN3 (high mobility group nucleosome-binding domain-containing protein 3), also known as TRIP7 (thyroid receptor-interacting protein 7), is a 99 amino acid member of the HMGN protein family. Localized to the nucleus, HMGN3 is believed to enhance transcription from chromatin templates by reducing the compactness of the chromatin fibers in the nucleosomes. HMGN3 also interacts with the ligand binding domain of the thyroid receptor. HMGN3 is induced by estrogen, and is abundantly expressed in skeletal muscle, kidney and heart with lower levels found in liver, pancreas and lung. HMGN3 is expressed as two isoforms produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HMGN3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with HMGN4: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of HMGN3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of HMGN3 of human origin |
| Entrez Gene | 9324 |
|---|
Application
Western blot analysis of HMGN3 expression in non-transfected: (A) and human HMGN3 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of HMGN3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with HMGN4: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
