Application
Western blot analysis of Synapsin Ia/b expression in non-transfected: (A) and mouse Synapsin Ia/b transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Synapsin Ia/b expression in rat cerebellum (A), rat brain (B) and mouse brain (C) tissue extracts.| Product Name | Synapsin Ia/b Antibody (H-170) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against amino acids 491-660 of Synapsin Ia/b of human origin |
| Modification Notes | Synapsins are synaptic vesicle-associated phosphoproteins that regulate synaptic vesicle exocytosis and may be involved in synaptogenesis. Evidence suggests that Synapsin I, Synapsin II and Synapsin IIIa are ATP-binding proteins that are regulated by Ca2+ and calmodulin binding. Ca2+ has been shown to stimulate ATP binding to Synapsin I, to have no effect on Synapsin II and to inhibit Synapsin III. Synapsin I and Synapsin II both undergo alternative splicing to produce two forms of each protein, Synapsin la and lb and Synapsin IIa and IIb, respectively. Synapsin III gives rise to at least three isoforms: Synapsin IIIa, IIIb and IIIc. Synapsin III plays unique roles both in early axon outgrowth and in the regulation of synaptic vesicle trafficking. In cultured mouse hippocampal neurons, Synapsin III is expressed early during development, with levels peaking seven days after plating and declining thereafter. Synapsin III is highly concentrated in growth cones. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| suitable control antibody: : sc-Synapsin Ia/b (m): 293T Lysate: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against amino acids 491-660 of Synapsin Ia/b of human origin |
|---|---|
| Tissue Specificity | raised against amino acids 491-660 of Synapsin Ia/b of human origin |
| Entrez Gene | 6853 |
|---|
Application
Western blot analysis of Synapsin Ia/b expression in non-transfected: (A) and mouse Synapsin Ia/b transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Synapsin Ia/b expression in rat cerebellum (A), rat brain (B) and mouse brain (C) tissue extracts.| Application Notes | suitable control antibody: : sc-Synapsin Ia/b (m): 293T Lysate: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
