| Product Name | AMID Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of AMID of human origin |
| Modification Notes | AMID (apoptosis-inducing factor (AIF)-like mitochondrion-associated inducer of death), also called p53-responsive gene 3 (PRG3), is a member of the FAD-dependent oxidoreductase family. AMID is a caspase independent pro-apoptotic flavoprotein with NAD(P)H oxidase activity localizing to the cytosol and associated with the outer mitochondrial membrane. AMID shares significant homology with AIF and NADH-oxidoreductases. It is expressed in most normal tissues and its expression is upregulated by p53. Two AMID isoforms exist due to alternative splicing. Isoform 1 is the full length protein and isoform 2 is missing amino acids 99-138. Isoform 2 also has an additional three amino acids inserted after residue 206. Overexpression of AMID leads to apoptosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of AIF-like mitochondrion-associated inducer of death of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of AMID of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of AMID of human origin |
| Entrez Gene | 84883 |
|---|
| Application Notes | recommended for detection of AIF-like mitochondrion-associated inducer of death of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
