| Product Name | ELOVL4 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 66-125 mapping near the N-terminus of ELOVL4 of human origin |
| Modification Notes | Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids-like 4 (ELOVL4) is expressed in ER in the retina and, to a lesser extent, in the brain. ELOVL4 is a possible photoreceptor-specific component of the fatty acid elongation system residing on the ER. Mutations in the ELOVL4 gene cause autosomal dominant Stargardt disease 3 (STGD3) and autosomal dominant Stargardt-like macular dystrophy (ADMD). STGD3 is a form of macular degen-eration that causes macular atrophy, decreased visual acuity and extensive fundus flecks in affected individuals. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ELOVL4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 66-125 mapping near the N-terminus of ELOVL4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 66-125 mapping near the N-terminus of ELOVL4 of human origin |
| Entrez Gene | 6785 |
|---|
| Application Notes | recommended for detection of ELOVL4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
