Application
Western blot analysis of Epiregulin expression in non-transfected: (A) and mouse Epiregulin transfected: (B) 293T whole cell lysates.| Product Name | Epiregulin Antibody (FL-162) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-162 representing full length Epiregulin of mouse origin |
| Modification Notes | Epiregulin (EPR, EREG), is an epidermal growth factor (EGF)-related growth regulating peptide which exhibits bifunctional properties in the regulation of cell growth (1–5). Epiregulin activates two members of the ErbB family of receptor tyrosine kinases, epidermal growth factor receptor (EGFR) and ErbB4 (1). Epiregulin is a potent vascular smooth muscle cell-derived mitogen induced by angiotensin II, endothelin-1 and thrombin (2). Epiregulin acts as an autocrine growth factor in human epidermal keratinocytes and is part of auto- and cross-induction mechanisms involving HB-EGF, amphiregulin and TGFalpha (3). Epiregulin is upregulated in pancreatic cancer and stimulates pancreatic cancer cell growth (4). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Epiregulin of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-162 representing full length Epiregulin of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-162 representing full length Epiregulin of mouse origin |
| Entrez Gene | 2069 |
|---|
Application
Western blot analysis of Epiregulin expression in non-transfected: (A) and mouse Epiregulin transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of Epiregulin of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
