| Product Name | Cyclophilin G Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 207-276 mapping within an internal region of Cyclophilin G of human origin |
| Modification Notes | Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Cyclophilin G, also known as CARS-Cyp (Clk-associating RS-cyclophilin), SRcyp (SR-cyclophilin), CASP10, PPIase G or Rotamase G, is a ubiquitously expressed member of the Moca family of cyclophilins. Localizing to the nucleus and, during interphase, nuclear speckles, Cyclophilin G contains an N-terminal cyclophilin-type domain, an acidic serine-rich region, five Cdc2-type phosphorylation sites and a series of serine-arginine repeats throughout the C-terminus. Cyclophilin G is phosphorylated during mitosis by the Cdc2-cyclin B complex, suggesting that its function is cell cycle-regulated. In addition, Cyclophilin G is capable of interacting with Pinin and the C-terminus of the largest subunit of RNA polymerase II (Pol II). Cyclophilin G may participate in pre-mRNA splicing by regulating the subnuclear localization of SR/SR-like protein family members. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Cyclophilin G of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 207-276 mapping within an internal region of Cyclophilin G of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 207-276 mapping within an internal region of Cyclophilin G of human origin |
| Application Notes | recommended for detection of Cyclophilin G of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
