Application
Western blot analysis of ACSS1 expression in non-transfected: (A) and mouse ACSS1 transfected: (B) 293T whole cell lysates.| Product Name | ACSS1 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ACSS1 of human origin |
| Modification Notes | ACSS1 (acyl-CoA synthetase short-chain family member 1), also known as ACAS2L or AceCS2L, is a 689 amino acid protein that localizes to the mitochondrial matrix and belongs to the ATP-dependent AMP-binding enzyme family. Functioning primarily as a cardiac enzyme, ACSS1 catalyzes the ATP-dependent conversion of acetate and CoA (coenzyme A) to acetyl-CoA, which is then utilized for the oxidation of acetate within the tricarboxylic acid cycle. ACSS1 is expressed as two alternatively spliced isoforms and is encoded by a gene which maps to chromosome 20. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ACSS1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ACSS2 also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ACSS1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ACSS1 of human origin |
| Entrez Gene | 84532 |
|---|
Application
Western blot analysis of ACSS1 expression in non-transfected: (A) and mouse ACSS1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of ACSS1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with ACSS2 also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
