Application
Western blot analysis of PRC expression in MIA PaCa-2 whole cell lysate (A), HeLa nuclear extract (B) and human liver tissue extract (C).| Product Name | PRC Antibody (Q-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of PRC of human origin |
| Modification Notes | PGC-1-related coactivator (PRC), also known as peroxisome proliferator-activated receptor gamma coactivator-related protein 1, is a 1,664 amino acid nuclear protein. PRC is involved in the coactivation of nuclear genes involved in mitochondrial biogenesis and cell growth. PRC acts as a transcriptional coactivator of CREB-1 and NRF-1 by interacting directly with CREB-1 and NRF-1 genes. Up-regulated by serum, PRC is present at high levels in skeletal muscle and heart and at moderate levels in kidney, spleen, thymus, intestine, placenta, lung, brain and colon. PRC has one RNA recognition motif (RRM) domain, which can bind directly to RNA. PRC is exists as two named isoforms produced by alternative splicing. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PRC isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other PRC family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of PRC of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of PRC of human origin |
| Entrez Gene | 23082 |
|---|
Application
Western blot analysis of PRC expression in MIA PaCa-2 whole cell lysate (A), HeLa nuclear extract (B) and human liver tissue extract (C).| Application Notes | recommended for detection of PRC isoforms 1 and 2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other PRC family members also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
