Application
Western blot analysis of TBG expression in mouse liver tissue extract.| Product Name | TBG Antibody (M-65) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 110-174 mapping within an internal region of TBG of mouse origin |
| Modification Notes | The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serpin family members include thyroxine-binding globulin precursor (TBG). TBG is a serum protein that transports thyroxine, carrying approximately 75% of circulating T4. Inherited de-fects in TBG are associated with three phenotypes based on the level of TBG in serum of affected hemizygous males: complete TBG deficiency (TBG-CD), partial TBG deficiency (TBG-PD) and TBG excess (TBG-E). TBG is expressed by the liver and secreted in plasma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TBG of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 110-174 mapping within an internal region of TBG of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 110-174 mapping within an internal region of TBG of mouse origin |
Application
Western blot analysis of TBG expression in mouse liver tissue extract.| Application Notes | recommended for detection of TBG of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
