Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic and membrane staining of glandular cells.| Product Name | Mac-2BP Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 84-383 mapping within an internal region of Mac-2BP of human origin |
| Modification Notes | Mac-2BP (Mac-2-binding protein), also known as LGALS3BP (lectin, galactoside-binding, soluble, 3 binding protein), 90K or BTBD17B, is a 585 amino acid protein that is secreted into the extracellular matrix and contains one SRCR domain, one BTB (POZ) domain and one BACK domain. Expressed ubiquitously, Mac-2BP exists as both a homodimer and a homomultimer and functions to promote Integrin-mediated cell adhesion, possibly playing a role in the stimulation of host defenses against tumor cells and viruses. Mac-2BP levels are elevated in HIV-infected hosts, further implicating Mac-2BP in immune system function. The gene encoding Mac-2BP maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Mac-2BP of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 84-383 mapping within an internal region of Mac-2BP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 84-383 mapping within an internal region of Mac-2BP of human origin |
| Entrez Gene | 3959 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate tissue showing cytoplasmic and membrane staining of glandular cells.| Application Notes | recommended for detection of Mac-2BP of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
