Application
Western blot analysis of Cacna2d1 expression in human fetal muscle tissue extract.| Product Name | Cacna2d1 Antibody (V-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of Cacna2d1 of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Modification Notes | Voltage-dependent calcium channels are essential for the release of neurotransmitters. Cacna2d1 (calcium channel, voltage-dependent, alpha 2/delta subunit 1), also known as CACNA2, CCHL2A, MHS3 or CACNL2A, is a 1,091 amino acid single-pass type I membrane protein that contains one VWFA domain and one cache domain. Expressed in skeletal muscle, aorta tissues and in the central nervous system (CNS), Cacna2d1 functions as an alpha-2/delta subunit of voltage-dependent calcium channels and plays an important role in calcium current density, as well as in excitation-contraction coupling. The Cacna2d1 precursor is proteolytically processed to produce two functional subunits, designated alpha-2-1 and delta-1, which are disulfide-linked to one another. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Cacna2d1 of mouse rat and human origin by WB IP and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of Cacna2d1 of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 781 |
|---|
Application
Western blot analysis of Cacna2d1 expression in human fetal muscle tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
