epitope mapping at the C-terminus of PCTAIRE-3 of human origin
Modification Notes
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks). Cdk proteins work in concert with cyclins to phosphorylate key substrates involved in cell cycle progression. Another family of proteins, Cdk inhibitors, also play a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Members of the Cdk family include Cdk2–Cdk8, PCTAIRE-1–3, PITALRE and PITSLRE. PCTAIRE-1, PCTAIRE-2 and PCTAIRE-3 comprise a subfamily of Cdc2-related serine/threonine kinases. PCTAIRE-1, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. PCTAIRE-2, also with expression in brain, may be important in terminally differentiated neurons. The human PCTAIRE-3 gene maps to chromosome 1q32.1.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of PCTAIRE-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping at the C-terminus of PCTAIRE-3 of human origin
Tissue Specificity
epitope mapping at the C-terminus of PCTAIRE-3 of human origin
Western blot analysis of PCTAIRE-3 expression in 293T whole cell lysate.
Application
Western blot analysis of PCTAIRE-3 expression in non-transfected: (A) and human PCTAIRE-3 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of PCTAIRE-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and bovine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.