| Product Name | GC-1 Antibody (S-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of GC-1 of human origin |
| Modification Notes | GC-1, also known as OLFM4 (olfactomedin-4) or GW112, is a 510 amino acid protein that is secreted into extracellular space and contains one olfactomedin-like domain. Expressed at high levels in prostate, colon and small intestine, with lower levels in bone marrow and stomach tissue, GC-1 exists as a homomultimer that functions as an anti-apoptotic factor that promotes cell growth and proliferation. Specifically functioning to assist in the S to G2/M phase transition and to facilitate cell adhesion, GC-1 interacts with Grim19 and plays an important role in the pathogenesis of pancreatic, stomach and colon cancer. The gene encoding GC-1 maps to human chromosome 13, which houses over 400 genes, such as BRCA2 and RB1, and comprises nearly 4% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of GC-1 of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of GC-1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of GC-1 of human origin |
| Entrez Gene | 10562 |
|---|
| Application Notes | recommended for detection of GC-1 of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
