Application
Western blot analysis of VPS41 expression in rat brain (A) and mouse brain (B) tissue extracts.| Product Name | VPS41 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 301-600 mapping within an internal region of VPS41 of human origin |
| Modification Notes | Vacuolar sorting proteins (VPSs) are required for proper trafficking of endocytic and biosynthetic proteins to the vacuole and play an important role in the budding process of cells. VPS41 (vacuolar protein sorting 41), also known as HVPS41, is an 854 amino acid protein that contains one clathrin repeat and one RING-type zinc finger. Existing as two alternatively spliced isoforms, designated short and long, VPS41 is required for proper vacuolar assembly and vacuolar traffic, playing a role in the formation and fusion of transport vesicles from the Golgi. The gene encoding VPS41 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of VPS41 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 301-600 mapping within an internal region of VPS41 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 301-600 mapping within an internal region of VPS41 of human origin |
| Entrez Gene | 27072 |
|---|
Application
Western blot analysis of VPS41 expression in rat brain (A) and mouse brain (B) tissue extracts.| Application Notes | recommended for detection of VPS41 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
