epitope mapping at the C-terminus of NDUFA6 of human origin
Modification Notes
NDUFA6 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6), also known as LYRM6 (LYR motif-containing protein 6), NADHB14 or B14, is a 128 amino acid protein that localizes to the matrix side of the mitochondrial membrane and belongs to the complex I LYR family. Existing as a subunit of the multi-protein membrane respiratory chain NADH dehydrogenase complex (Complex I), NDUFA6 functions as an accessory protein that facilitates the transfer of electrons from NADH to the respiratory chain. The gene encoding NDUFA6 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of NDUFA6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other NDUFA family members also reactive with additional species, including canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping at the C-terminus of NDUFA6 of human origin
Tissue Specificity
epitope mapping at the C-terminus of NDUFA6 of human origin
Western blot analysis of NDUFA6 expression in HeLa whole cell lysate.
Application
Western blot analysis of NDUFA6 expression in 293T whole cell lysate.
Application Notes
recommended for detection of NDUFA6 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other NDUFA family members also reactive with additional species, including canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.