epitope mapping within an internal region of CRP2BP of human origin
Modification Notes
CRP2BP (cysteine-rich protein 2-binding protein, CSRP2-binding protein) is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of CRP2BP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of CRP2BP of human origin
Tissue Specificity
epitope mapping within an internal region of CRP2BP of human origin
Western blot analysis of CRP2BP expression in non-transfected: (A) and mouse CRP2BP transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of CRP2BP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.