| Product Name | PPP1R6 Antibody (P-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of PPP1R6 of human origin |
| Modification Notes | In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. PPP1R6 (protein phosphatase 1, regulatory subunit 6), also known as PPP1R3D in humans and Ppp1r3d in rodents, is a 299 amino acid protein that contains one CBM21 (carbohydrate binding type-21) domain and exists as a regulatory subunit of the PP1 holoenzyme. Expressed ubiquitously with highest expression in heart and skeletal muscle, PPP1R6 functions as a glycogen-targeting subunit of PP1 and participates in cell division, glycogen metabolism and protein synthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PPP1R6 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PPP1R4 also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PPP1R6 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PPP1R6 of human origin |
| Entrez Gene | 5509 |
|---|
| Application Notes | recommended for detection of PPP1R6 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with PPP1R4 also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
