| Product Name | p160 Rock-1 Antibody (D-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of p160 Rock-1 of human origin |
| Modification Notes | Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures, including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described and include the Rho-activated serine/threonine kinases Rock-1 and Rock-2 (also referred to as Roka, for Rho-associated coil-containing protein kinase). Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase. p160 Rock-1, also known as LOC727758, is a 167 amino acid protein that shares a high degree of sequence homology with Rock-1 and may be involved in regulating Rho function. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of p160 Rock-1 and Rock-1 of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of p160 Rock-1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of p160 Rock-1 of human origin |
| Entrez Gene | 6093 |
|---|
| Application Notes | recommended for detection of p160 Rock-1 and Rock-1 of human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
